Our students have published their research in a wide variety of high-impact scientific journals. Please see below a list of all SBM CDT research publications.

P9. Harnessing triaryloxonium ions for aryne generation.
Smith, O., Hindson, M., Sreenithya, A., Tataru, V., Paton, R., Burton, J. and Smith, M. D.
ChemRxiv, 2023, Preprint.
P8. Taming non-classical carbocations to control small ring reactivity.
McNamee, R. E., Frank, N., Christensen, K, Duarte, F. and Anderson, E. A.
ChemRxiv, 2023, Preprint.
P7. Precise, orthogonal remote-control of cell-free systems using photocaged nucleic acids.
Mazzotti, G., Hartmann, D. and Booth, M.
ChemRxiv, 2023, Preprint.
P6. Dynamical nonequilibrium molecular dynamics simulations identify allosteric sites and positions associated with drug resistance in the SARS-CoV-2 main protease.
Chan, H.T.H., Oliveira, A.S.F., Schofield, C.J., Mulholland, A.J. and Duarte, F.
bioRxiv, 2022, Preprint.
P4. Blue light-activatable DNA for remote control of cell-free logic gates and synthetic cells.
Hartmann, D., Chowdhry, R., Smith, J. and Booth, M.
ChemRxiv, 2022, Preprint.
P3. Engineering cellular communication between light-activated synthetic cells and bacteria.
Smith, J. M., Hartmann, D. and Booth, M. J.
bioRxiv, 2022, Preprint.
P2. Catalytic Enantioselective Nucleophilic Desymmetrisation of Phosphonate Esters.
Formica, M., Rogova, T., Shi, H., Sahara, N., Farley, A., Christensen, K., Duarte, F. and Dixon, D. J.
ChemRxiv, 2021, Preprint.
Stacks Image 10357
P1. Intact nucleosomal context enables chromodomain reader MRG15 to distinguish H3K36me3 from -me2.
Faulkner, S., Couturier, A. M., Josephson, B., Watts, T., Davis, B. G. and Esashi, F.
bioRxiv, 2020, Preprint.

248. A photoswitchable solvatochromic dye for probing membrane ordering by RESOLFT super-resolution microscopy.
Frawley, A., Leslie, K., Wycisk, V., Galiani, S., Shrestha, D., Eggeling, C. and Anderson, H. L.
ChemRxiv, 2023, Preprint.
2023, e202300125.
Stacks Image 10473
247. Mobile Molecules: Reactivity Profiling Guides Faster Movement on a Cysteine Track.
Bo, Z., Lim, Z. H., Duarte, F., Bayley, H., Qing, Y.
Angew. Chem. Int. Ed., 2023, e202300890.
246. Bifunctional Iminophosphorane-Catalyzed Enantioselective Nitroalkane Addition to Unactivated α,β-Unsaturated Esters.
Rozsar, D., Farley, A., McLauchlan, I., Shennan, B. A., Yamazaki, K. and Dixon, D. J.
ChemRxiv, 2022, Preprint.
Angew. Chem. Int. Ed.,
2023, e202303391.
Stacks Image 10467
245. Control of stereogenic oxygen in a helically chiral oxonium ion.
Smith, O., Popescu, M., Hindson, M., Paton, R., Burton, J. and Smith, M. D.
ChemRxiv, 2022, Preprint.
2023, 615, 430.
Stacks Image 10369
244. Visible Light Photoredox-Catalyzed Decarboxylative Alkylation of 3-Aryl-Oxetanes and Azetidines via Benzylic Tertiary Radicals and Implications of Benzylic Radical Stability.
Dubois, M. A. J., Rojas, J. J., Sterling, A. J., Broderick, H. C., Smith, M. A., White, A. J. P., Miller, P. W., Choi, C., Mousseau, J. J., Duarte, F. and Bull, J. A.
J. Org. Chem.,
2023, Article ASAP.
Stacks Image 10456
243. Enantioselective Total Synthesis of (−)-Himalensine A via a Palladium and 4-Hydroxyproline Co-catalyzed Desymmetrization of Vinyl-bromide-tethered Cyclohexanones.
Kučera, R., Ellis, S. E., Yamazaki, K., Hayward Cooke, J., Chekshin, N., Christensen, K. E., Hamlin, T. A. and Dixon, D. J.
J. Am. Chem. Soc.,
2023, 145, 5422.
Stacks Image 10453
242. Catalytic enantioselective 6𝝿 photocyclization of acrylanilides
Jones, B., Solon, P., Popescu, M., Du, J.-Y., Paton, R. and Smith, M. D.
ChemRxiv, 2022, Preprint.
J. Am. Chem. Soc.,
2023, 145, 171.
Stacks Image 10439
241. Enantioselective synthesis of atropisomeric indoles via iron-catalysed oxidative cross-coupling
Surgenor, R., Liu, X., Keenlyside, M., Myers, W. and Smith M. D.
ChemRxiv, 2021, Preprint.
Nat. Chem.,
2023, 15, 357.
Stacks Image 10005
240. Alcohols as efficient intermolecular initiators for a highly stereoselective polyene cyclisation cascade.
Aynetdinova, D., Jacques, R., Christensen, K. and Donohoe, T. J.
Chem. Eur. J., 2023, 29, e202203732.
Stacks Image 10399

239. Total Synthesis and Structure Confirmation of (E) and (Z)-Ocellenyne.
Hicks, H. B., Brown, D. S., Chan, H. S. S., Sousa, B. A., Christensen, K. E. and Burton, J. W.
Org. Lett., 2022, 24, 9174.
Stacks Image 10321
238. Photo-switchable anion binding and catalysis with a visible light responsive halogen bonding receptor.
Kerckhoffs, A., Moss, I. and Langton, M. J.
Chem. Commun., 2023, 59, 51.
Stacks Image 10393
237. Recent advances in the dearomative functionalisation of heteroarenes.
Kratena, N., Marinic, B. and Donohoe, T. J.
Chem. Sci., 2022, 13, 14213.
Stacks Image 10387
236. Rapid and scalable halosulfonylation of strain-release reagents.
Pickford, H. D., Ripenko, V., McNamee, R. E., Holovchuk, S., Thompson, A. L., Smith, R. C., Mykhailiuk, P. K. and Anderson, E. A.
ChemRxiv, 2022, Preprint.
Angew. Chem. Int. Ed.,
2023, 62, e202213508.
Stacks Image 10381
235. Rhodium-Catalyzed [2 + 2 + 2] Cyclotrimerizations of Yndiamides with Alkynes.
Smith, P. J., Tong, Z., Ragus, J., Solon, P., Shimkin, K. W. and Anderson, E. A.
Org. Lett., 2022, 24, 7522.
Stacks Image 10351
234. Enantioselective oxidation of unactivated C–H bonds in cyclic amines by iterative docking-guided mutagenesis of P450BM3 (CYP102A1).
Zhang, Y., Xiong, Z., Li, Y., Wilson, M., Christensen, K. E., Jaques, E., Hernández-Lladó, P., Robertson, J. and Wong, L. L.
Nat. Synth.,
2022, 1, 936.
Stacks Image 10345
232. Synthesis of meta-substituted arene bioisosteres from [3.1.1]propellane.
Frank, N., Nugent, J., Shire, B.R., Pickford, H. D., Rabe, P., Sterling, A. J., Zarganes-Tzitzikas, T., Grimes, T., Thompson, A. L., Smith, R. C., Schofield, C. J., Brennan, P. E., Duarte, D. and Anderson, E. A.
ChemRxiv, 2022, Preprint.
2022, 611, 721.
231. Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33α and TRIM33β Bromodomains.
Sekirnik, A., Reynolds, J., See, L., Bluck, J., Scorah, A., Tallant, C., Lee, B., Leszczynska, K., Grimley, R., Storer, R. I., Malattia, M, Crespillo, S., Caria, S., Duclos, S., Hammond, E. M., Knapp, S., Morris, G. M., Duarte, F., Biggin, P., and Conway, S. J.
ChemRxiv, 2022, Preprint.
ACS Chem. Biol.,
2022, 17, 2753.
Stacks Image 10327
229. Towards fully optimised and automated ESR spectroscopy.
Verstraete, J.-B., Yong, J. R. J., Goodwin, D. L., Myers, W. K. and Foroozandeh, M.
Chem. Commun., 2022, 58, 10715.
Stacks Image 10315
228. A Vicinal Diol Approach for the Total Synthesis of Molestin E, ent-Sinulacembranolide A and ent-Sinumaximol A.
Hoff, O., Kratena, N., Aynetdinova, D., Christensen, K. E. and Donohoe, T. J.
Chem. Eur. J., 2022, 28, e202202464.
Stacks Image 10309
227. Counterion-Mediated Enantioconvergent Synthesis of Axially Chiral Medium Rings.
Du, J.-Y., Balan, T., Claridge, T. D. W. C and Smith, M. D.
J. Am. Chem. Soc., 2022, 144, 14790.
Stacks Image 10303
226. N-Sulfinyl-O-(tert-Butyl)Hydroxylamine.
Davies, T. Q. and Willis, M. C.
In Encyclopedia of Reagents for Organic Synthesis. John Wiley & Sons, 2022.
Stacks Image 10238
225. An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides.
Baker, Y.R., Thorpe, C., Chen, J., Poller, L. M., Cox, L., Kumar, P., Lim, W. F., Lie, L., McClorey, G., Epple, S., Singleton, D., McDonough, M. A., Hardwick, J. S., Christensen, K. E., Wood, M. J. A., Hall, J. P., El-Sagheer, A. H., and Brown, T.
Nat. Commun., 2022, 13, 4036.
224. Alcohols as Alkylating Agents in the Cation-Induced Formation of Nitrogen Heterocycles.
Cox, L., Zhu, Y., Smith, P. J., Christensen, K. E., Sidera Portela, M. and Donohoe, T. J.
Angew. Chem. Int. Ed., 2022, 61, e202206800.
Stacks Image 10285
223. Branching out: redox strategies towards the synthesis of acyclic α-tertiary ethers.
Shennan, B. D. A., Berheci, D., Crompton, J. L., Davidson, T. A., Field, J. L., Williams, B. A and Dixon, D. J.
Chem. Soc. Rev., 2022, 51, 5878.
Stacks Image 10279
222. Modular Two-Step Route to Sulfondiimidamides.
Zhang, Z.-X., Bell, C., Ding, M. and Willis, M. C.
J. Am. Chem. Soc., 2022, 144, 11851.
Stacks Image 10273
221. An autonomously oscillating supramolecular self-replicator.
Howlett, M.G., Engwerda, A.H.J., Scanes, R.J.H. and Fletcher, S. P.
Nat. Chem., 2022, 14, 805.
Stacks Image 10267
220. Evolution of the Dearomative Functionalization of Activated Quinolines and Isoquinolines: Expansion of the Electrophile Scope.
Kischkewitz, M., Marinic, B., Kratena, N., Lai, Y., Hepburn, H. B., Dow, M., Christensen, K. E. and Donohoe,T. J.
Angew. Chem. Int. Ed., 2022, 61, e202204682.
Stacks Image 10261
219. Photocatalytic Late- Stage Functionalization of Sulfonamides via Sulfonyl Radical Intermediates.
Tilby, M.J ., Dewez, D. F., Pantaine, L. R. E., Hall, A., Martínez-Lamenca, C. and Willis, M. C.
ACS Catal., 2022, 12, 6060.
Stacks Image 10255
218. Extension of hydrogen borrowing alkylation reactions for the total synthesis of (−)-γ-lycorane.
Hall, C., Marriott, I., Christensen, K., Day, A., Goundry, W. and Donohoe, T. J.
Chem. Commun., 2022, 58, 4966.
Stacks Image 10249
217. [18F]Difluorocarbene for Positron Emission Tomography.
Sap, J.B.I., Meyer, C.F., Ford, J., Straathof, N., Dürr, A., Lelos, M., Paisey, S., Mollner, T., Hell, S., Trabanco, A., Genicot, C., am Ende, C., Paton, R. S., Tredwell, M. and Gouverneur, V..
Nature, 2022, 606, 102.
216. Transition Metal-Free, Visible Light-Mediated Radical Cyclisation of Malonyl Radicals onto 5-Ring Heteroaromatics.
Hernández-Lladó, P., Garrec, K., Schmitt, D. and Burton, J.
Adv. Synth. Catal., 2022, 364, 1724.
Stacks Image 10229
215. Reading and erasing of the phosphonium analogue of trimethyllysine by epigenetic proteins.
Kamps, J.J.A.G., Belle, R., Poater, J., Kumar, K., Pieters, B., Salah, E., Claridge, T. D. W., Paton, R., S., Bickelhaupt, F. M., Kawamura, A., Schofield, C. J. and Mecinović, J.
Commun. Chem., 2022, 5, 27.
Stacks Image 10223
214. Asymmetric Azidation under Hydrogen Bonding Phase-Transfer Catalysis: A Combined Experimental and Computational Study.
Wang, J., Horwitz, M. A., Dürr, A. B., Ibba, F., Pupo, G., Gao, Y., Ricci, P., Christensen, K. E., Pathak, T. P., Claridge, T. D. W. C., Lloyd-Jones, G. C., Paton, R. S. and Gouverneur, V.
J. Am. Chem. Soc., 2022, 144, 4572.
Stacks Image 10217
213. A Silyl Sulfinylamine Reagent Enables the Modular Synthesis of Sulfonimidamides via Primary Sulfinamides.
Ding, M., Zhang, Z.-X., Davies, T. Q. and Willis, M. C.
Org. Lett., 2022, 24, 1711.
Stacks Image 10211
212. Amino-oxetanes as amide isosteres by an alternative defluorosulfonylative coupling of sulfonyl fluorides.
Rojas, J. J., Croft, R. A., Sterling, A. J., Briggs, E. L., Antermite, D., Schmitt, D., Blagojevic, L., Haycock, P., White, A., Duarte, F., Choi, C., Mousseau, J. and Bull, J. A.
Nat. Chem., 2022, 14, 160.
Stacks Image 10203
211. DABSO – A Reagent to Revolutionize Organosulfur Chemistry.
Andrews, J. A. and Willis, M. C.
Synthesis, 2022, 54, 1695.
Stacks Image 10197
210. Modular Pulse Program Generation for NMR Supersequences.
Yong, J. R. J., Kupce, E. and Claridge, T. D. W.
Anal. Chem., 2022, 94, 2271.
Stacks Image 10191
209. Diverse saturated heterocycles from a hydroacylation/conjugate addition cascade.
Iwumene, N. U. N., Moseley, D. F., Pullin, R. C. and Willis, M. C.
Chem. Sci., 2022, 13, 1504.
Stacks Image 10180
208. Characterisation of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification.
Baddock, H., Brolih, S., Yosaatmadja, Y., Ratnaweera, M., Bielinski, M., Swift, L., Cruz-Migoni, A., Fan, H., Keown, J., Walker, A., Morris, G. M., Grimes, J., Fodor, E., Schofield, C. J., Gileadi, O. and McHugh, P. J.
bioRxiv, 2020, Preprint.
Nucleic Acids Res.,
2022, 50, 1484.
207. A New Organocatalytic Desymmetrization Reaction Enables the Enantioselective Total Synthesis of Madangamine E.
Shiomi, S., Shennan, B., Yamazaki, K., Fuentes de Arriba, Á.L., Vasu, D., Hamlin, T. A. and Dixon, D. J.
ChemRxiv, 2021, Preprint.
J. Am. Chem. Soc.,
2022, 144, 1407.
Stacks Image 10177
206. Bifunctional Iminophosphorane-Catalyzed Enantioselective Sulfa-Michael Addition to Unactivated α,β-Unsaturated Amides.
Rozsar, D., Formica, M., Yamazaki, K., Hamlin, T. and Dixon, D. J.
ChemRxiv, 2021, Preprint.
J. Am. Chem. Soc.,
2022, 144, 1006.
Stacks Image 9885

205. Synthesis and Applications of Polysubstituted Bicyclo[1.1.0]butanes.
McNamee, R. E.
, Thompson, A. L. and Anderson E. A.
J. Am. Chem. Soc., 2021, 143, 21246.
Stacks Image 10143
204. Synthesis and Application of Constrained Amidoboronic Acids Using Amphoteric Boron-Containing Building Blocks.
Soor, H. S., Diaz, D. B., Tsui, K. Y., Calvopiña, K., Bielinski, M., Tantillo, D. J., Schofield, C. J. and Yudin, A. K.
J. Org. Chem., 2022, 87, 94.
Stacks Image 10171
203. Single photon double and triple ionization of allene.
Ideböhn, V., Sterling, A. J., Wallner, M., Olsson, E., Squibb, R. J., Miniotaite, U., Forsmalm, E., Forsmalm, M., Stranges, S., Dyke, J. M., Duarte, F., Eland, J. H. D., and Feifel, R.
Phys. Chem. Chem. Phys., 2022, 24, 786.
Stacks Image 10161
202. First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53.
Nowak, R., Tumber, A., Hendrix, E., Ansari, M., Sabatino, M., Antonini, L., Andrijes, R., Salah, E., Mautone, N., Pellegrini, F., Simelis, K., Kawamura, A., Johansson, C., Passeri, D., Pellicciari, R., Ciogli, A., Del Bufalo, D., Ragno, R., Coleman, M., Trisciuoglio, D., Mai, A., Oppermann, U., Schofield, C. J. and Rotili, D.
J. Med. Chem., 2021, 64, 17031.
Stacks Image 10149
201. Lactone Backbone Density in Rigid Electron-Deficient Semiconducting Polymers Enabling High n-type Organic Thermoelectric Performance.
Alsufyani, M., Stoeckel, M.-A., Chen, X., Thorley, K., Hallani, R.K., Puttisong, Y., Ji, X., Meli, D., Paulsen, B.D., Strzalka, J., Regeta, K., Combe, C., Chen, H., Tian, J., Rivnay, J., Fabiano, S. and McCulloch, I.
Angew. Chem. Int. Ed., 2022, 61, e202113078.
Stacks Image 10155
200. Parallel NMR Supersequences: Ten Spectra in a Single Measurement.
Kupče, E., Yong, J. R. J., Widmalm, G. and Claridge, T. D. W.
JACS Au, 2021, 1, 1892.
Stacks Image 10131
199. Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen-Substituted Bicyclo[1.1.1]pentanes.
Livesley, S., Sterling, A.J., Robertson, C.M., Goundry, W.R.F., Morris, J.A., Duarte, F. and Aïssa, C.
Angew. Chem. Int. Ed., 2022, 61, e202111291.
Stacks Image 10137
198. Benzenemethanamine, α,α-Diphenyl-N-Sulfinyl-.
Tilby, M. and Willis, M. C.
In Encyclopedia of Reagents for Organic Synthesis. John Wiley & Sons, 2021.
Stacks Image 10125
197. Synthesis of α-Quaternary Bicyclo[1.1.1]pentanes through Synergistic Organophotoredox and Hydrogen Atom Transfer Catalysis.
Nugent, J., Sterling, A. J., Frank, N., Mousseau, J. J. and Anderson, E. A.
Org. Lett., 2021, 23, 8628.
Stacks Image 10101
196. Sulfinates from Amines: A Radical Approach to Alkyl Sulfonyl Derivatives via Donor–Acceptor Activation of Pyridinium Salts.
Andrews, J., Pantaine, L., Palmer, C. F., Poole, D. L. and Willis, M. C.
Org. Lett., 2021, 23, 8488.
Stacks Image 10119
195. A Three-Component Ugi-Type Reaction of N-Carbamoyl Imines Enables a Broad Scope Primary α-Amino 1,3,4-Oxadiazole Synthesis.
Matheau-Raven, D., Boulter, E., Rogova, T. and Dixon, D. J.
Org. Lett., 2021, 23, 8209.
Stacks Image 10107
194. Red-shifted tetra-ortho-halo-azobenzenes for photo-regulated transmembrane anion transport.
Kerckhoffs, A., Bo, Z., Penty, S. E., Duarte, F. and Langton, M. J.
Org. Biomol. Chem., 2021, 19, 9058.
Stacks Image 9981
193. Exploiting Configurational Lability in Aza-Sulfur Compounds for the Organocatalytic Enantioselective Synthesis of Sulfonimidamides.
Tilby, M. J., Dewez, D. F., Hall, A., Martínez Lamenca, C. and Willis, M. C.
Angew. Chem. Int. Ed., 2021, 60, 25680.
Stacks Image 10095
192. A New 1,5-Disubstituted Triazole DNA Backbone Mimic with Enhanced Polymerase Compatibility.
Epple, S., Modi, A., Baker, Y. R., WÈ©grzyn, E., Traoré, D., Wanat, P., Tyburn, A., Shivalingam, A., Taemaitree, L., El-Sagheer, A. and Brown, T.
J. Am. Chem. Soc., 2021, 143, 16293.
Stacks Image 10089
191. Azine-N-oxides as effective controlling groups for Rh-catalysed intermolecular alkyne hydroacylation.
Moseley, D. F., Kalepua, J. and Willis, M. C.
Chem. Sci., 2021, 12, 13068.
Stacks Image 10083
190. Discovery of SARS-CoV-2 Mpro Peptide Inhibitors from Modelling Substrate and Ligand Binding.
Chan, H. T. H., Moesser, M., Walters, R. K., Malla, T. R., Twidale, R. M., John, T., Deeks, H. M., Johnston-Wood, T., Mikhailov, V., Sessions, R. B., Dawson, W., Salah, E., Lukacik, P., Strain-Damerell, C., Owen, D., Nakajima, T., Swiderek, K., Lodola, A., Moliner, V., Glowacki, D. R., Walsh, M. A., Schofield, C. J., Genovese, L., Shoemark, D., Mulholland, A. J., Duarte, F. and Morris, G. M.
bioRxiv, 2021, Preprint.
Chem. Sci.,
2021, 12, 13686.
Stacks Image 10077
188. Switchable, Reagent-Controlled Diastereodivergent Photocatalytic Carbocyclisation of Imine-Derived α-Amino Radicals.
Maitland, J. A. P., Leitch, J. A., Yamazaki, K., Christensen, K. E., Cassar, D. J., Hamlin, T. A. and Dixon, D. J.
Angew. Chem. Int. Ed., 2021, 60, 24116.
Stacks Image 10065
187. X-ray free-electron laser studies reveal correlated motion during isopenicillin N synthase catalysis.
Rabe, P., Kamps, J. J. A. G., Sutherlin, K., Linyard, J., Aller, P., Pham, C., Makita, H., Clifton, I., McDonough, M., Leissing, T., Shutin, D., Lang, P., Butryn, A., Brem, J., Gul, S., Fuller, F., Kim, I-S., Cheah, M., Fransson, T., Bhowmick, A., Young, I., O’Riordan, L., Brewster, A., Pettinati, I., Doyle, M., Joti, Y., Owada, S., Tono, K., Batyuk, A., Hunter, M., Alonso-Mori, r., Bergmann, U., Owen, R., Sauter, N., Claridge, T. D. W., Robinson, C. V., Yachandra, V. K., Yano, J., Kern, J. F., Orville, A. M. and Schofield, C. J.
Sci. Adv., 2021, 7, eabh0250.
186. Selection between Competing Self-Reproducing Lipids: Succession and Dynamic Activation.
Howlett, M. G., Scanes, R. J. H. and Fletcher, S. P.
JACS Au, 2021, 1, 1355.
Stacks Image 10059
185. A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family.
Baddock, H., Newman, J., Yosaatmadja, Y., Bielinski, M., Schofield, C. J., Gileadi, O and McHugh, P. J.
Nucleic Acids Res., 2021, 49, 9294.
184. Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition.
Yosaatmadja, Y., Baddock, H., Newman, J., Bielinski, M., Gavard, A., Mukhopadhyay, S., Dannerfjord, A., Schofield, C. J., McHugh, P. J. and Gileadi, O.
bioRxiv, 2021, Preprint.
Nucleic Acids Res.,
2021, 49, 9310.
183. Synthesis of Polysubstituted Fused Pyrroles by Gold-Catalyzed Cycloisomerization/1,2-Sulfonyl Migration of Yndiamides.
Smith, P. J., Jiang, Y., Tong, Z., Pickford, H. D., Christensen, K. E., Nugent, J. and Anderson, E. A.
Org. Lett., 2021, 23, 6547.
Stacks Image 9761
182. Base-Activated Latent Heteroaromatic Sulfinates as Nucleophilic Coupling Partners in Palladium-Catalyzed Cross-Coupling Reactions.
Cook, X. A. F., Pantaine, L. R. E., Blakemore, D. C., Moses, I. B., Sach, N. W., Shavnya, A. and Willis, M. C.
Angew. Chem. Int. Ed., 2021, 60, 22461.
Stacks Image 10041
181. On-the-Fly, Sample-Tailored Optimization of NMR Experiments.
Yong, J. R. J. and Foroozandeh, M.
Anal. Chem., 2021, 93, 10735.
Stacks Image 10035
180. Supramolecular chemistry in lipid bilayer membranes.
Kerckhoffs, A., Bickerton, L., Johnson, T. and Langton, M. J.
Chem. Sci., 2021, 12, 11252.
Stacks Image 10029
179. Artificial nucleic acid backbones and their applications in therapeutics, synthetic biology and biotechnology.
Epple, S., El-Sagheer, A. H. and Brown, T.
Emerg. Top. Life Sci., 2021, 5, 691.
178. An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography.
Butryn, A., Simon, P., Aller, P., Hinchliffe, P., Massad, R., Leen, G., Tooke, C., Bogacz, I., Kim, I-S., Bhowmick, A., Brewster, A. S., Devenish, N., Brem, J., Kamps, J., Lang, P., Rabe, P., Axford, D., Beale, J., Davy, B., Ebrahim, A., Orlans, J., Storm, S., Zhou, T., Owada, S., Tanaka, R., Tono, K., Evans, G., Owen, R., Houle, F., Sauter, N., Schofield, C. J., Spencer, J., Yachandra, V., Yano, J., Kern, J. and Orville, A. M.
Nat. Commun., 2021, 12, 4461.
177. A General Iridium-Catalyzed Reductive Dienamine Synthesis Allows a Five-Step Synthesis of Catharanthine via the Elusive Dehydrosecodine.
Gabriel. P., Almehmadi, Y., Rong Wong, Z. and Dixon, D. J.
J. Am. Chem. Soc., 2021, 143, 10828.
Stacks Image 10011
176. Controlling Intramolecular Interactions in the Design of Selective, High-Affinity, Ligands for the CREBBP Bromodomain.
Brand, M., Clayton, J., Moroglu, M., Schiedel, M., Picaud, S., Bluck, J., Skwarska, A., Bolland, H., Chan, A., Laurin, C., Scorah, A., See, L., Rooney, T., Andrews, K., Fedorov, O., Perell, G., Kalra, P., Vinh, K., Cortopassi, W., Heitel, P., Christensen, K., Cooper, R., Paton, R., Pomerantz, W., Biggin, P., Hammond, E. M., Filippakopoulos, P. and Conway, S. J.
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84. Convergent Total Syntheses of (−)‐Rubriflordilactone B and (−)‐pseudo‐Rubriflordilactone B
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80. Bicyclic Boronate VNRX-5133 Inhibits Metallo- and Serine-β-Lactamases
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79. Modular Sulfondiimine Synthesis Using a Stable Sulfinylamine Reagent
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77. Retooling Asymmetric Conjugate Additions for Sterically Demanding Substrates with an Iterative Data-Driven Approach
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74. Intramolecular Aldol Ring Closures of Cysteine Derivatives Leading to Densely Functionalised Pyroglutamates
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73. Total Synthesis of Berkeleylactone A
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72. Dehydrodieugenol B derivatives as antiparasitic agents: Synthesis and biological activity against Trypanosoma cruzi
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71. A General Copper-Catalyzed Synthesis of Ynamides from 1,2-Dichloroenamides​
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69. Synthesis of Enantioenriched α‐Chiral Bicyclo[1.1.1]pentane​​
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66. Dithiane-Directed Rh(III)-Catalyzed Amidation of Unactivated C(sp3)-H Bonds
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62. Chemical Probes​
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58. Chemical epigenetics: the impact of chemical‐ and chemical biology techniques on bromodomain target validation​
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55. Non‐Hydrolytic β‐Lactam Antibiotic Fragmentation by L,D‐Transpeptidases and Serine β‐Lactamase Cysteine Variants
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54. Enantioselective rhodium-catalysed insertion of trifluorodiazoethanes into tin hydrides
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53. Design, Synthesis and Characterization of Covalent KDM5 Inhibitors
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52. A structure-based approach towards identification of inhibitory fragments for eleven-nineteen-leukemia protein (ENL)
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49. Copper-catalysed synthesis of alkylidene 2-pyrrolinone derivatives from the combination of α-keto amides and alkynes
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48. Discovery of an MLLT1/3 YEATS Domain Chemical Probe
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47. Enantioselective Silver-Catalyzed Cascade Synthesis of Fused Lactone and Lactam Oxazolines
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46. Post-translational site-selective protein backbone α-deuteration
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45. Principles and Applications of Fragment-based Drug Discovery for Chemical Probes
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44. Bifunctional Iminophosphorane Catalysed Enantioselective Sulfa-Michael Addition of Alkyl Thiols to Alkenyl Benzimidazoles
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43. Photocatalytic Reverse Polarity Povarov Reaction
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42. Polyyne formation via skeletal rearrangement induced by atomic manipulation
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41. A Bench-Stable Transfer Reagent for the Synthesis of Trifluoromethyl-sulfonimidamides from Sulfinamides
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40. A transient self-assembling self-replicator
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39. The Plant Cysteine Oxidases from Arabidopsis thaliana are kinetically tailored to act as oxygen sensors
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37. Synthesis and Applications of Highly Functionalized 1-Halo-3-Substituted Bicyclo[1.1.1]pentanes
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35. BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability
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34. Asymmetric nucleophilic fluorination under hydrogen bonding phase-transfer catalysis
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33. An enamine controlling group for rhodium-catalyzed intermolecular hydroacylation
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32. Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2
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31. Molecular machines for catalysis
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30. Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases
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29. Spironaphthoxazine switchable dyes for biological imaging
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27. Synthesis of Polyynes Using Dicobalt Masking Groups
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26. Detecting Mechanochemical Atropisomerization within an STM Break Junction
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25. Total synthesis of (−)-himalensine A
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24. Hexafluoroisopropanol as a highly versatile solvent
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23. One-pot, Three-Component Sulfonimidamide Synthesis exploiting the Sulfinylamine Reagent N-Sulfinyltritylamine, TrNSO
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22. Copper-Catalyzed Synthesis and Applications of Yndiamide
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21. Enantioselective Conjugate Addition Catalyzed by a Copper Phosphoramidite Complex: Computational and Experimental Exploration of Asymmetric Induction
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20. Crotonases - Nature's Exceedingly Convertible Catalysts
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19. Exploiting Carbonyl Groups to Control Intermolecular Rhodium-Catalyzed Alkene and Alkyne Hydroacylation
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17. Unexpected Interactions between Alkyl Straps and Pyridine Ligands in Sulfur-Strapped Porphyrin Nanorings
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13. Neutral iodotriazole foldamers as tetradentate halogen bonding anion receptors
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12. Discovery of a PCAF Bromodomain Chemical Probe
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10. A Cascade Strategy Enables a Total Synthesis of (+/-)-Morphine
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9. Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity
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8. Chemical Probes and Inhibitors of Bromodomains outside the BET family
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7. Photoswitchable Spiropyran Dyads for Biological Imaging
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6. Cp2ZrMeCl: A Reagent for Asymmetric Methyl Addition
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5. Recent Applications in Natural Product Synthesis of Dihydrofuran and -pyran Formation by Ring-closing Alkene Metathesis
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4. Organocatalytic Enantioselective Desymmetrisation
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3. Cascade Polycyclizations in Natural Product Synthesis
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2. Strategic Application and Transformation of ortho-Disubstituted Phenyl and Cyclopropyl Ketones to Expand the Scope of Hydrogen Borrowing Catalysis
Frost, J. R., Cheong, C. B., Akhtar, W. M., Caputo, D. F. J., Stevenson, N. G. and Donohoe, T. J.
J. Am. Chem. Soc. 2015, 137, 15664.
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1. Active-Metal Template Synthesis of a Halogen-Bonding Rotaxane for Anion Recognition
Langton, M. J., Xiong, Y. and Beer, P. D.
Chem. Eur. J. 2015, 21, 18910.
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Department of Chemistry
Chemistry Research Laboratory
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Oxford, OX1 3TA
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